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Sci. Signal., 12 May 2009
[DOI: 10.1126/scisignal.2000146]

Supplementary Materials for:

TRPM1 Forms Ion Channels Associated with Melanin Content in Melanocytes

Elena Oancea,* Joris Vriens, Sebastian Brauchi, Janice Jun, Igor Splawski, David E. Clapham

*To whom correspondence should be addressed. E-mail: Elena_Oancea{at}Brown.edu

This PDF file includes:

  • Fig. S1. Mouse TRPM1 isoforms.
  • Fig. S2. Lanthanum blocks endogenous TRPM1 current in B16-F1 and B16-F10 mouse melanocytes.
  • Fig. S3. Characterization of 92+TRPM1 and 109+TRPM1 current in SK-Mel19 human melanocytes.
  • Fig. S4. Cellular localization of GFP-(109+TRPM1) in HEK cells and tyrosinase mRNA abundance in HEM cells treated with TRPM1 miRNA.
  • Movie S1. Dynamic localization of GFP-(70+TRPM1) in human melanoma cells.

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Other Supplementary Material for this manuscript includes the following:

Movie S1 (mov format)

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Size: 800 KB


Citation: E. Oancea, J. Vriens, S. Brauchi, J. Jun, I. Splawski, D. E. Clapham, TRPM1 forms ion channels associated with melanin content in melanocytes. Sci. Signal. 2, ra21 (2009).

© 2009 American Association for the Advancement of Science


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