Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. STKE, 26 June 2001
[DOI: 10.1126/stke.2001.88.re1]

Animation 2B. Synaptic Vesicle Release through a Putative V0-like Pore Animation

If the fusion pore were a proteinaceous complex composed of trans-complexes of V0-like sectors from the synaptic vesicle and the plasma membranes, fusion would correspond to the calcium-calmodulin-dependent opening of the V0-like pore and the reverse reaction to the closing of this pore.

As in the slow track, the proton pump would restore the electrochemical gradient, allowing for the uptake of neurotransmitter into the vesicle, which can undergo further rounds of exocytosis.

Press the "Continue" button to advance through the animation.

Citation: T. Galli, V. Haucke, Cycling of Synaptic Vesicles: How Far? How Fast! Science's STKE (2001),;2001/88/re1.

This movie is in Macromedia Flash Player format. If you have difficulty viewing the movie, please consult the following information from Macromedia :

Macintosh Specific Installation

Windows Specific Installation

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882