Sci. STKE, 2 April 2002
Animation 1. A Model for Local Regulation of Translation Near Synapses Animation
RNA granules (GR) contain mRNA, ribosomes and ribosomal subunits, and other components. Some RNA granules are docked, whereas others are motile with oscillatory movements. A stimulus induces reorganization and positional readjustment of granules in relation to a cluster of synapses and local release of stored mRNA/ribosomes/translation factors. P, preexisting polysomes; R, preexisting clusters of ribosomes; MT, microtubules.
Citation: K. Kosik, A. Krichevsky, The Message and the Messenger: Delivering RNA in Neurons. Sci. STKE 2002, pe16 (2002).
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