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Sci. STKE, 21 June 2005
[DOI: 10.1126/stke.2892005tr18]

Nuclear Transactivators and Repressors
(PowerPoint Slides)

Zhen-Qiang Pan*

Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY 10029, USA.


*Contact information. E-mail: zhen-qiang.pan{at}


Slides are provided for a class covering the mechanism and regulation of eukaryotic gene transcription machinery and are part of the course “Cell Signaling Systems: A Course for Graduate Students.” The slides begin with an overview of eukaryotic gene transcription and then proceed to describe mechanisms of transcription by RNA polymerase II, the action of Mediator, and enhancer-promoter communication during gene activation.

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Educational Details

Learning Resource Type: PowerPoint slides

Context: Undergraduate upper division, graduate, professional (degree program)

Intended Users: Teacher, learner

Intended Educational Use: Teach, learn, plan

Discipline: Biochemistry, Molecular Biology, Structural Biology

Keywords: eukaryotic gene transcription, RNA Polymerase II, Mediator, TFII (transcription factor for polymerase II)

Technical Details

Format: PowerPoint (ppt)

Size: 2.3 MB

Requirements: Microsoft PowerPoint

Limits for Use

Cost: Free

Rights: This material may be downloaded for noncommercial, course-teaching purposes only, provided credit to STKE is included by listing the citation for the Teaching Resource.


Citation: Z.Q. Pan, Nuclear transactivators and repressors. Sci. STKE 2005, tr18 (2005).

© 2005 American Association for the Advancement of Science

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