Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Sci. Signal., 5 January 2010
[DOI: 10.1126/scisignal.2000551]

Supplementary Materials for:

Impaired αIIbβ3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1

Margitta Elvers, David Stegner, Ina Hagedorn, Christoph Kleinschnitz, Attila Braun, Marijke E. J. Kuijpers, Michael Boesl, Qin Chen, Johan W. M. Heemskerk, Guido Stoll, Michael A. Frohman, Bernhard Nieswandt*

*To whom correspondence should be addressed. E-mail: bernhard.nieswandt{at}virchow.uni-wuerzburg.de

This PDF file includes:

  • Table S1. Blood cell counts and platelet glycoprotein expression of Pld1−/− mice.
  • Fig. S1. Generation of PLD1-deficient mice.
  • Fig. S2. Impaired αIIbβ3 activation in Pld1−/− platelets under stirring conditions.
  • Fig. S3. Botrocetin induces vWF binding, but not integrin activation, in platelets.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size: 303 KB


Citation: M. Elvers, D. Stegner, I. Hagedorn, C. Kleinschnitz, A. Braun, M. E. J. Kuijpers, M. Boesl, Q. Chen, J. W. M. Heemskerk, G. Stoll, M. A. Frohman, B. Nieswandt, Impaired αIIbβ3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1. Sci. Signal. 3, ra1 (2010).

© 2010 American Association for the Advancement of Science


To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882