Distinct Signal Codes Generate Dendritic Cell Functional Plasticity

Kazuhiko Arima, Norihiko Watanabe, Shino Hanabuchi, Mikyoung Chang, Shao-Cong Sun, Yong-Jun Liu*

*To whom correspondence should be addressed. E-mail: yjliu{at}mdanderson.org

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• Fig. S1. R848 is a weaker inducer of STAT5 phosphorylation than is TSLP.
• Fig. S2. TSLP, but not IL-7 or IL-4, is capable of inducing the activation of a range of STAT proteins in mDCs.
• Fig. S3. TSLP induces the phosphorylation of ERK, JNK, and Akt in mDCs.
• Fig. S4. TSLP increases the abundance of NF-κB target molecules in mDCs.
• Fig. S5. PCR gel electrophoresis data for the ChIP assays shown in Fig. 3E.
• Fig. S6. TSLP is not a dominant-negative regulator of the production of IL-12.

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