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Sci. Signal., 23 February 2010
[DOI: 10.1126/scisignal.2000634]

Supplementary Materials for:

Apoptotic Cells Activate the "Phoenix Rising" Pathway to Promote Wound Healing and Tissue Regeneration

Fang Li, Qian Huang, Jiang Chen, Yuanlin Peng, Dennis R. Roop, Joel S. Bedford, Chuan-Yuan Li*

*To whom correspondence should be addressed. E-mail: Chuan.Li{at}

This PDF file includes:

  • Fig. S1. Validation of the bioluminescence assay as a measure of cell proliferation.
  • Fig. S2. Caspase 7 in the dying cells contributes to their stimulation of progenitor cell proliferation.
  • Fig. S3. Immunofluorescence staining of cytokeratin 6 and cytokeratin 14 during skin wound healing in wild-type and Casp3–/– mice.
  • Fig. S4. Skin wound healing is compromised in Casp7–/– mice.
  • Fig. S5. Caspase 7 deficiency compromises liver regeneration.
  • Fig. S6. Calcium-independent phospholipase A2 in the proliferation-stimulating effects of dying cells.

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Citation: F. Li, Q. Huang, J. Chen, Y. Peng, D. R. Roop, J. S. Bedford, C.-Y. Li, Apoptotic Cells Activate the "Phoenix Rising" Pathway to Promote Wound Healing and Tissue Regeneration. Sci. Signal. 3, ra13 (2010).

© 2010 American Association for the Advancement of Science

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