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Sci. Signal., 1 June 2010
[DOI: 10.1126/scisignal.2000758]

Supplementary Materials for:

Transient ATM Kinase Inhibition Disrupts DNA Damage–Induced Sister Chromatid Exchange

Jason S. White, Serah Choi, Christopher J. Bakkenist*

*To whom correspondence should be addressed. E-mail: bakkenistcj{at}upmc.edu

This PDF file includes:

  • Fig. S1. KU60019 is another reversible inhibitor of ATM activity.
  • Table S1. Dose-dependent and KU55933-dependent increase in chromosome aberrations in IMR90 fibroblasts.
  • Table S2. Dose-dependent and NU7441-dependent increase in chromosome aberrations in IMR90 fibroblasts.
  • Table S3. Chromosome aberrations induced by 2 Gy IR in late-S and G2-phase IMR90 fibroblasts (+15 to +75 min post-IR).
  • Table S4. Chromosome aberrations induced by 2 Gy IR in late-S and G2-phase IMR90 cells (+15 to +225 min post-IR).
  • Table S5. Chromosome aberrations induced by 2 Gy IR in Artemis-defective cells after inhibition of ATM for 1 hour.

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Technical Details

Format: Adobe Acrobat PDF

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Citation: J. S. White, S. Choi, C. J. Bakkenist, Transient ATM Kinase Inhibition Disrupts DNA Damage–Induced Sister Chromatid Exchange. Sci. Signal. 3, ra44 (2010).

© 2010 American Association for the Advancement of Science


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