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Sci. Signal., 8 June 2010
[DOI: 10.1126/scisignal.2000769]

Supplementary Materials for:

β-Arrestin–Biased Agonism of the Angiotensin Receptor Induced by Mechanical Stress

Kriti Rakesh, ByungSu Yoo, Il-Man Kim, Natasha Salazar, Ki-Seok Kim, Howard A. Rockman*

*To whom correspondence should be addressed. E-mail: h.rockman{at}duke.edu

This PDF file includes:

  • Table S1. Quantification of receptor internalization and β-arrestin translocation.
  • Fig. S1. βARs are not involved in stretch-mediated signaling.
  • Fig. S2. Time course of stretch-mediated ERK phosphorylation.
  • Fig. S3. Increased markers of apoptosis in mouse hearts treated with losartan.

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Technical Details

Format: Adobe Acrobat PDF

Size: 457 KB


Citation: K.Rakesh, B. Yoo, I.-M. Kim, N. Salazar, K.-S. Kim, H. A. Rockman, β-Arrestin–Biased Agonism of the Angiotensin Receptor Induced by Mechanical Stress. Sci. Signal. 3, ra46 (2010).

© 2010 American Association for the Advancement of Science


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