Vav1-Mediated Scaffolding Interactions Stabilize SLP-76 Microclusters and Contribute to Antigen-Dependent T Cell Responses

Nicholas R. Sylvain, Ken Nguyen, Stephen C. Bunnell*

*To whom correspondence should be addressed. E-mail: stephen.bunnell{at}tufts.edu

This PDF file includes:

• Fig. S1. Effects of Vav1 mutants on TCR-induced Ca²⁺ flux.
• Fig. S2. Mutations that affect the catalytic core of the Vav1 GEF.
• Table S1. Effect of knockdown of Vav1 on SLP-76 microcluster dynamics.
• Table S2. List of primers used to generate the various Vav1 mutations.
• Movies S1 to S16 legend.
  

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© 2011 American Association for the Advancement of Science