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Sci. Signal., 19 July 2011
[DOI: 10.1126/scisignal.2001765]

Supplementary Materials for:

PreTCR and TCRγδ Signal Initiation in Thymocyte Progenitors Does Not Require Domains Implicated in Receptor Oligomerization

Juliet Mahtani-Patching, Joana F. Neves, Dick John Pang, Kostadin V. Stoenchev, Ana M. Aguirre-Blanco, Bruno Silva-Santos, Daniel J. Pennington*

*To whom correspondence should be addressed. E-mail: d.pennington{at}qmul.ac.uk

This PDF file includes:

  • Fig. S1. pTα chains that lack regions implicated in preTCR oligomerization initiate signaling that complements pTα deficiency.
  • Fig. S2. Signal initiation from TCRΔIγΔIδ induces the expression of γδ cell signature genes.
  • Fig. S3. A truncated TCRγ chain lacking both extracellular Ig-like domains pairs with pTα to initiate signaling.

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Technical Details

Format: Adobe Acrobat PDF

Size: 313 KB


Citation: J. Mahtani-Patching, J. F. Neves, D. J. Pang, K. V. Stoenchev, A. M. Aguirre-Blanco, B. Silva-Santos, D. J. Pennington, PreTCR and TCRγδ Signal Initiation in Thymocyte Progenitors Does Not Require Domains Implicated in Receptor Oligomerization. Sci. Signal. 4, ra47 (2011).

© 2011 American Association for the Advancement of Science


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