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Sci. Signal., 14 February 2012
[DOI: 10.1126/scisignal.2001963]

Supplementary Materials for:

Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist

William S. Bowen, Laurie A. Minns, David A. Johnson, Thomas C. Mitchell, Melinda M. Hutton, Jay T. Evans*

*To whom correspondence should be addressed. E-mail: jay.t.evans{at}gskbio.com

This PDF file includes:

  • Fig. S1. Comparison of the production of MyD88- and TRIF-dependent cytokines and chemokines by human monocytes treated with CRX-527, CRX-547, Re595 LPS, or sMLA.
  • Fig. S2. CRX-547 stimulates the production of lower amounts of IL-1β by human PBMCs than does CRX-527.

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Technical Details

Format: Adobe Acrobat PDF

Size: 300 KB


Citation: W. S. Bowen, L. A. Minns, D. A. Johnson, T. C. Mitchell, M. M. Hutton, J. T. Evans, Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist. Sci. Signal. 5, ra13 (2012).

© 2012 American Association for the Advancement of Science


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