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Sci. Signal., 5 February 2013
[DOI: 10.1126/scisignal.2003638]

Supplementary Materials for:

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

Robert B. Hamanaka, Andrea Glasauer, Paul Hoover, Shuangni Yang, Hanz Blatt, Andrew R. Mullen, Spiro Getsios, Cara J. Gottardi, Ralph J. DeBerardinis, Robert M. Lavker, Navdeep S. Chandel*

*To whom correspondence should be addressed. E-mail: nav{at}northwestern.edu

This PDF file includes:

  • Fig. S1. Analysis of epidermal apoptosis and epidermal thickness in control and TFAM cKO skin.
  • Fig. S2. Sensitivity of control keratinocyte differentiation to exogenous H2O2 and inhibition of mitochondrial calcium uptake.
  • Fig. S3. Analysis of cellular signaling pathways in control and TFAM cKO keratinocytes.
  • Fig. S4. Sensitivity of Notch signaling to ROS during keratinocyte differentiation.
  • Fig. S5. Sensitivity of Wnt–β-catenin signaling to ROS in epidermal keratinocytes.

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Technical Details

Format: Adobe Acrobat PDF

Size: 475 KB


Citation: R. B. Hamanaka, A. Glasauer, P. Hoover, S. Yang, H. Blatt, A. R. Mullen, S. Getsios, C. J. Gottardi, R. J. DeBerardinis, R. M. Lavker, N. S. Chandel, Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development. Sci. Signal. 6, ra8 (2013).

© 2013 American Association for the Advancement of Science


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