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Science 319 (5870): 1627-1628

Copyright © 2008 by the American Association for the Advancement of Science

A Protoplasmic Kiss to Remember

Martin Korte

During establishment of long-term memory, protein synthesis, regulated by neurotrophins, affects the morphology of synaptic structures.

Zoological Institute, Division of Cellular Neurobiology, TU Braunschweig, D-38106 Germany. E-mail: m.korte{at}

An Increase in Basal BDNF Provokes Hyperactivation of the Akt-Mammalian Target of Rapamycin Pathway and Deregulation of Local Dendritic Translation in a Mouse Model of Down's Syndrome.
J. A. Troca-Marin, A. Alves-Sampaio, and M. L. Montesinos (2011)
J. Neurosci. 31, 9445-9455
   Abstract »    Full Text »    PDF »
Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase M{zeta} (PKM{zeta}).
S. Sajikumar and M. Korte (2011)
PNAS 108, 2551-2556
   Abstract »    Full Text »    PDF »
Synaptic Activity Controls Dendritic Spine Morphology by Modulating eEF2-Dependent BDNF Synthesis.
C. Verpelli, G. Piccoli, C. Zibetti, A. Zanchi, F. Gardoni, K. Huang, D. Brambilla, M. Di Luca, E. Battaglioli, and C. Sala (2010)
J. Neurosci. 30, 5830-5842
   Abstract »    Full Text »    PDF »

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