Sci. STKE, 11 July 2000
Review PDZ Domains
Defined tertiary structures allow proteins to bind to and communicate with other proteins. The PDZ domain, identified in several signaling proteins located at the plasma membrane, binds to a (T/S)XV motif found in the COOH-terminus of other proteins. Garner et al. review the role of the PDZ domain in protein complex assembly in pre- and postsynaptic membranes, and the formation of signaling "active zones."
Garner, C.C., Nash, J. and Huganir, R.L. (2000) PDZ domains in synapse assembly and signalling. Trends Cell Biol. 10: 274-280. [Online Journal]
Citation: PDZ Domains. Sci. STKE 2000, tw10 (2000).
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