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Science 293 (5528): 228-229

Copyright © 2001 by the American Association for the Advancement of Science

IMMUNOLOGY:
Tampering with the Immune System

Pamela L. Schwartzberg

Tight regulation of the immune system is essential to ensure an appropriate immune response to pathogens and to prevent inappropriate immune responses that could lead to autoimmune disease. As Schwartzberg explains in her Perspective, new work shows that the Tyro-3 family of receptor tyrosine kinases may be important for regulating the activity of the immune system's antigen-presenting cells, which are important for presenting antigen to lymphocytes and for clearing up cellular debris that could provoke an autoimmune response.

The author is at the National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA. E-mail: pams{at}nhgri.nih.gov

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882