Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Logo for

Science 296 (5574): 1819-1820

Copyright © 2002 by the American Association for the Advancement of Science

DEVELOPMENT:
Putting the Brakes on Regeneration

Lisa McKerracher and Benjamin Ellezam

The recalcitrance of nerves in the central nervous system (CNS) to regenerate has thwarted efforts to treat patients with spinal cord and other CNS injuries. In their Perspective, McKerracher and Ellezam discuss new findings (Goldberg et al.) revealing that a switch from an axonal to a dendritic growth mode during development may carry over into the adult, preventing CNS neurons from regenerating their axons.


The authors are in the Département de Pathologie et Biologie Cellulaire, Université de Montréal, 2900 Edouard-Montpetit, Montréal, Québec, H3T 1J4 Canada. E-mail: mckerral{at}patho.umontreal.ca



To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882