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Phytohormones such as gibberellins are known to promote plant growth, but it is unclear how they do this. In a Perspective, Harberd discusses new work (Sasaki et al.) that reveals the biochemical basis of the relief-of-restraint model of plant growth regulation. A gibberellin signal promotes proteasomal degradation of DELLA proteins, which normally restrain plant growth.
The author is at the John Innes Centre, Norwich, Norfolk NR4 7UH, UK. E-mail: nicholas.harberd{at}bbsrc.ac.uk
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In Science Magazine
REPORTS
Akie Sasaki, Hironori Itoh, Kenji Gomi, Miyako Ueguchi-Tanaka, Kanako Ishiyama, Masatomo Kobayashi, Dong-Hoon Jeong, Gynheung An, Hidemi Kitano, Motoyuki Ashikari, and Makoto Matsuoka (21 March 2003) Science299 (5614), 1896.
[DOI: 10.1126/science.1081077] |Abstract »|Full Text »|PDF »|Supporting Online Material »
Fruit Growth in Arabidopsis Occurs via DELLA-Dependent and DELLA-Independent Gibberellin Responses.
S. Fuentes, K. Ljung, K. Sorefan, E. Alvey, N. P. Harberd, and L. Ostergaard (2012)
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157, 2120-2130
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23, 1337-1351
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Releasing the brakes of plant growth: how GAs shutdown DELLA proteins.
The Cold-Inducible CBF1 Factor-Dependent Signaling Pathway Modulates the Accumulation of the Growth-Repressing DELLA Proteins via Its Effect on Gibberellin Metabolism.
P. Achard, F. Gong, S. Cheminant, M. Alioua, P. Hedden, and P. Genschik (2008)
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20, 2117-2129
|Abstract »|Full Text »|PDF »
Global Identification of DELLA Target Genes during Arabidopsis Flower Development.
X. Hou, W.-W. Hu, L. Shen, L. Y. C. Lee, Z. Tao, J.-H. Han, and H. Yu (2008)
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147, 1126-1142
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Y. Gan, H. Yu, J. Peng, and P. Broun (2007)
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145, 1031-1042
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The plant stress hormone ethylene controls floral transition via DELLA-dependent regulation of floral meristem-identity genes.
P. Achard, M. Baghour, A. Chapple, P. Hedden, D. Van Der Straeten, P. Genschik, T. Moritz, and N. P. Harberd (2007)
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104, 6484-6489
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P. Achard, L. Liao, C. Jiang, T. Desnos, J. Bartlett, X. Fu, and N. P. Harberd (2007)
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143, 1163-1172
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Gibberellin Mobilizes Distinct DELLA-Dependent Transcriptomes to Regulate Seed Germination and Floral Development in Arabidopsis.
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S. Ishikawa, M. Maekawa, T. Arite, K. Onishi, I. Takamure, and J. Kyozuka (2005)
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46, 79-86
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P. Achard, A. Herr, D. C. Baulcombe, and N. P. Harberd (2004)
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The Arabidopsis Mutant sleepy1gar2-1 Protein Promotes Plant Growth by Increasing the Affinity of the SCFSLY1 E3 Ubiquitin Ligase for DELLA Protein Substrates.
X. Fu, D. E. Richards, B. Fleck, D. Xie, N. Burton, and N. P. Harberd (2004)
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|Abstract »|Full Text »|PDF »
Gibberellin regulates Arabidopsis floral development via suppression of DELLA protein function.
H. Cheng, L. Qin, S. Lee, X. Fu, D. E. Richards, D. Cao, D. Luo, N. P. Harberd, and J. Peng (2004)
Development
131, 1055-1064
|Abstract »|Full Text »|PDF »
Ethylene Regulates Arabidopsis Development via the Modulation of DELLA Protein Growth Repressor Function.
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