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Science 300 (5617): 261-263

Copyright © 2003 by the American Association for the Advancement of Science

PLANT SCIENCE:
Hexokinase, Jack-of-All-Trades

Wolf B. Frommer, Waltraud X. Schulze, Sylvie Lalonde

Certain enzymes have dual functions having both catalytic and signaling activities. To this group can now be added plant hexokinases, as Frommer and colleagues discuss in their Perspective. Elegant work with Arabidopsis mutants reveals that plant hexokinases not only phosphorylate glucose but also sense glucose levels and participate in the glucose signaling pathway.

W. B. Frommer and S. Lalonde are in the Department of Plant Physiology, Zentrum für Molekularbiologie der Pflanzen, Universitat Tübingen, D-72076 Tübingen, Germany. E-mail: frommer{at}zmbp.uni-tübingen.de W. X. Schulze is at the Protein Interaction Laboratory, Department of Biochemistry and Molecular Biology, University of Southern Denmark, 5230 Odense, Denmark.

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