Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
In some simple protozoans and unicellular algae, the cell cycle clock is strongly influenced by the circadian clock, such that mitotic cell division takes place only at certain times of the day. Now, as Schibler reports in his Perspective, new work on regenerating liver cells in mice (Matsuo et al.) reveals that the cell cycle clock of mammalian cells is also under the yoke of the master circadian oscillator.
The author is in the Department of Molecular Biology, University of Geneva, CH-1211 Geneva 4, Switzerland. E-mail: ueli.schibler{at}molbio.unige.ch
The editors suggest the following Related Resources on Science sites:
In Science Magazine
RESEARCH ARTICLES
Takuya Matsuo, Shun Yamaguchi, Shigeru Mitsui, Aki Emi, Fukuko Shimoda, and Hitoshi Okamura (10 October 2003) Science302 (5643), 255.
[DOI: 10.1126/science.1086271] |Abstract »|Full Text »|PDF »|Supporting Online Material »
Vasoactive Intestinal Polypeptide Entrains Circadian Rhythms in Astrocytes.
L. Marpegan, T. J. Krall, and E. D. Herzog (2009)
J Biol Rhythms
24, 135-143
|Abstract »|PDF »
Light-Dependent Regulation of Cell Division in Ostreococcus: Evidence for a Major Transcriptional Input.
M. Moulager, A. Monnier, B. Jesson, R. Bouvet, J. Mosser, C. Schwartz, L. Garnier, F. Corellou, and F.-Y. Bouget (2007)
Plant Physiology
144, 1360-1369
|Abstract »|Full Text »|PDF »
Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging.
