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IMMUNOLOGY: The Robin Hood of Antigen Presentation
Gennaro De Libero
Immunologists continue to unveil a startling diversity in the antigenic repertoire of T cells, which now rivals that of B cells. In his Perspective, De Libero discusses new work (Zhou et al., Moody et al.) that adds lipopeptide antigens to the list of T cell immunogens and reveals how lipid antigens are handled in antigen-presenting cells and then presented to T cells.
The author is in the Department of Research, University Hospital Basel, Basel CH-4031, Switzerland. E-mail: gennaro.delibero{at}unibas.ch
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In Science Magazine
REPORTS
Dapeng Zhou, Carlos Cantu, III, Yuval Sagiv, Nicolas Schrantz, Ashok B. Kulkarni, Xiaoyang Qi, Don J. Mahuran, Carlos R. Morales, Gregory A. Grabowski, Kamel Benlagha, Paul Savage, Albert Bendelac, and Luc Teyton (23 January 2004) Science303 (5657), 523.
[DOI: 10.1126/science.1092009] |Abstract »|Full Text »|PDF »|Supporting Online Material »
REPORTS
D. Branch Moody, David C. Young, Tan-Yun Cheng, Jean-Pierre Rosat, Carme Roura-mir, Peter B. O'Connor, Dirk M. Zajonc, Andrew Walz, Marvin J. Miller, Steven B. Levery, Ian A. Wilson, Catherine E. Costello, and Michael B. Brenner (23 January 2004) Science303 (5657), 527.
[DOI: 10.1126/science.1089353] |Abstract »|Full Text »|PDF »|Supporting Online Material »
