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STRUCTURAL BIOLOGY: Enhanced: The p75 NGF Receptor Exposed
Niccoló Zampieri and Moses V. Chao
Neurotrophins such as nerve growth factor (NGF) are secreted growth factors that are important for neuronal survival and plasticity. In their Perspective, Zampieri and Chao discuss a new study (He and Garcia) that highlights some unusual features about the binding of NGF to the p75 receptor.
The authors are in the Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, Departments of Cell Biology, Physiology, and Neuroscience, New York University School of Medicine, New York, NY 10016, USA. E-mail: chao{at}saturn.med.nyu.edu
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