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CELL BIOLOGY: Tickling Macrophages, a Serious Business
Stephanie Züllig and Michael O. Hengartner
Failure to remove apoptotic cells and cell debris has been linked to the development of autoimmunity. In their Perspective, Züllig and Hengartner discuss a study from Nagata and colleagues that identifies a crucial bridging protein, MFG-E8, as essential for the removal of apoptotic cells (Hanayama et al.).
The authors are at the Institute of Molecular Biology, University of Zürich, CH-8057 Zürich, Switzerland. E-mail: michael.hengartner{at}molbio.unizh.ch
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In Science Magazine
REPORTS
Rikinari Hanayama, Masato Tanaka, Kay Miyasaka, Katsuyuki Aozasa, Masato Koike, Yasuo Uchiyama, and Shigekazu Nagata (21 May 2004) Science304 (5674), 1147.
[DOI: 10.1126/science.1094359] |Abstract »|Full Text »|PDF »|Supporting Online Material »
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