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Science 304 (5677): 1610-1611

Copyright © 2004 by the American Association for the Advancement of Science

DEVELOPMENTAL BIOLOGY:
Hox Genes in the Limb: A Play in Two Acts

Jacqueline Deschamps

The development of the tetrapod limb depends on complex cascades of gene expression. In her Perspective, Deschamps reports on a new study (Zákány et al.) that dissects the expression patterns and functions of the HoxD gene cluster during the early stages of limb bud development in the mouse.


The author is at the Hubrecht Laboratory, Uppsalalaan 8, 3584CT Utrecht, Netherlands. E-mail: jacqueli{at}niob.knaw.nl


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Appendage expression driven by the Hoxd Global Control Region is an ancient gnathostome feature.
I. Schneider, I. Aneas, A. R. Gehrke, R. D. Dahn, M. A. Nobrega, and N. H. Shubin (2011)
PNAS 108, 12782-12786
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