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Science 305 (5680): 50-52

Copyright © 2004 by the American Association for the Advancement of Science

Let There Be (NADH) Light

Luc Pellerin and Pierre J. Magistretti

The consumption of glucose in the brain has been attributed principally to the activity of neurons. In their Perspective, Pellerin and Magistretti discuss an elegant imaging study (Kasischke et al.) that dissects the metabolic activity of rat hippocampal slices and reveals the intertwined metabolisms of neurons and astrocytes (a type of glial cell) in the brain.

The authors are at the Institut de Physiologie, 1005 Lausanne, Switzerland. E-mail: luc.pellerin{at}; pierre.magistretti{at}

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