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Science 305 (5683): 482-483

Copyright © 2004 by the American Association for the Advancement of Science

Epileptic Neurons Go Wireless

Kevin Staley

Neuroscientists have long been puzzled by the fact that prolonged epileptic seizures facilitate future seizures. In his Perspective, Staley discusses a recent study in a rat model of temporal lobe epilepsy (Bernard et al.), which shows that a contributory factor to this facilitation is the loss of inhibitory K+ ion currents called A currents.

The author is in the Department of Neurology and Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262, USA. E-mail: kevin.staley{at}

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