Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Logo for

Science 306 (5700): 1277-

Copyright © 2004 by the American Association for the Advancement of Science

MEDICINE:
Estrogen's Ties to COX-2 May Explain Heart Disease Gender Gap

Jennifer Couzin

Estrogen recruits the enzyme COX-2 in the blood vessels of mice, according to research published online by Science this week (www.sciencemag.org/cgi/content/abstract/1103333), raising the possibility that COX-2 inhibitors--including Vioxx, which was yanked off the market in September because of cardiovascular risks--might be particularly hazardous to females.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Women's health and gender-based clinical trials on etoricoxib: methodological gender bias.
E. Chilet-Rosell, M. T. Ruiz-Cantero, and J. F. Horga (2009)
J Public Health 31, 434-445
   Abstract »    Full Text »    PDF »
CRHR1 Polymorphisms Predict Bone Density in Survivors of Acute Lymphoblastic Leukemia.
T. S. Jones, S. C. Kaste, W. Liu, C. Cheng, W. Yang, K. G. Tantisira, C.-H. Pui, and M. V. Relling (2008)
J. Clin. Oncol. 26, 3031-3037
   Abstract »    Full Text »    PDF »

To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882