Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Logo for

Science 307 (5717): 1886-1888

Copyright © 2005 by the American Association for the Advancement of Science

MOLECULAR BIOLOGY:
Signal Processing in Single Cells

Farren J. Isaacs, William J. Blake, James J. Collins

Gene networks can be designed that enable exploration of how gene expression is regulated, an example of synthetic biology. In their Perspective, Isaacs et al. discuss two studies (Rosenfeld et al., Pedraza and van Oudenaarden) that combine modeling with experiments to analyze gene networks in bacteria.


F. J. Isaacs is at the Lipper Center for Computational Genetics and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. W. J. Blake and J. J. Collins are at the Center for BioDynamics and Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA. E-mail: jcollins{at}bu.edu


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Single cell resolution in regulation of gene expression.
O. G. Bahcall (2014)
Mol Syst Biol 1, 2005.0015
   Full Text »    PDF »

To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882