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Science 307 (5717): 1886-1888

Copyright © 2005 by the American Association for the Advancement of Science

Signal Processing in Single Cells

Farren J. Isaacs, William J. Blake, James J. Collins

Gene networks can be designed that enable exploration of how gene expression is regulated, an example of synthetic biology. In their Perspective, Isaacs et al. discuss two studies (Rosenfeld et al., Pedraza and van Oudenaarden) that combine modeling with experiments to analyze gene networks in bacteria.

F. J. Isaacs is at the Lipper Center for Computational Genetics and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. W. J. Blake and J. J. Collins are at the Center for BioDynamics and Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA. E-mail: jcollins{at}

Single cell resolution in regulation of gene expression.
O. G. Bahcall (2014)
Mol Syst Biol 1, 2005.0015
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