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Science 308 (5723): 800-801

Copyright © 2005 by the American Association for the Advancement of Science

Matching at the Synapse

Scott M. Thompson

Neurons in the brain make many thousands of connections (synapses) with other neurons. In a Perspective, Thompson discusses a technical tour-de-force (Koester and Johnson) that reveals subtle differences in the characteristics of neurotransmitter release, which depend on the type of postsynaptic target cells with which the presynaptic cell connects.

The author is in the Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201-1559, USA. E-mail: sthom003{at}

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