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DEVELOPMENTAL BIOLOGY: Enhanced: Less Steroids Make Bigger Flies
Kirst King-Jones and Carl S. Thummel
It has long been known that animal growth is achieved primarily during juvenile stages and terminates after sexual maturation. In their Perspective, King-Jones and Thummel discuss how the findings of Colombani et al. in this issue provide important new insights into how this coordination of growth and maturation is achieved through steroid and insulin signaling pathways.
The authors are in the Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. E-mail: kirst{at}genetics.utah.edu; carl.thummel{at}genetics.utah.edu
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REPORTS
Julien Colombani, Laurence Bianchini, Sophie Layalle, Emilie Pondeville, Chantal Dauphin-Villemant, Christophe Antoniewski, Clément Carré, Stéphane Noselli, and Pierre Léopold (28 October 2005) Science310 (5748), 667.
[DOI: 10.1126/science.1119432] |Abstract »|Full Text »|PDF »|Supporting Online Material »
