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Science 312 (5771): 207-208

Copyright © 2006 by the American Association for the Advancement of Science

Managing Associations Between Different Chromosomes

Charalampos G. Spilianakis and Richard A. Flavell

Genes present on different chromosomes can be coordinately expressed through a transcription regulatory factor that brings them together in a region of active transcription in the nucleus.

The authors are in the Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; E-mail: richard.flavell{at}

Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells.
T. H. Vu, A. H. Nguyen, and A. R. Hoffman (2010)
Hum. Mol. Genet. 19, 901-919
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A Genomewide Survey Argues That Every Zygotic Gene Product Is Dispensable for the Initiation of Somatic Homolog Pairing in Drosophila.
J. R. Bateman and C.-t. Wu (2008)
Genetics 180, 1329-1342
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The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells.
C. W. Tang, A. Maya-Mendoza, C. Martin, K. Zeng, S. Chen, D. Feret, S. A. Wilson, and D. A. Jackson (2008)
J. Cell Sci. 121, 1014-1024
   Abstract »    Full Text »    PDF »

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