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NEUROSCIENCE: Regulating Energy Balance: The Substrate Strikes Back
Jeffrey S. Flier
Hormones and dietary nutrients control appetite and metabolism by acting on the brain, where the signals they elicit promote hunger or satiety. Neurons in the hypothalamus integrate these signals to regulate energy balance.
The author is in the Division of Endocrinology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA 02215, USA. E-mail: jflier{at}bidmc.harvard.edu
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Daniela Cota, Karine Proulx, Kathi A. Blake Smith, Sara C. Kozma, George Thomas, Stephen C. Woods, and Randy J. Seeley (12 May 2006) Science312 (5775), 927.
[DOI: 10.1126/science.1124147] |Abstract »|Full Text »|PDF »|Supporting Online Material »
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