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MICROBIOLOGY: Bacteria Seize Control by Acetylating Host Proteins
Carolyn A. Worby and Jack E. Dixon
The plague-causing bacterium Yersinia pestis injects toxic proteins into its hosts' cells. One of these interferes with the host's secretion of a protective factor by adding acetyl groups to a signaling kinase, blocking its activation.
The authors are in the Departments of Pharmacology, Cellular and Molecular Medicine, and Chemistry and Biochemistry, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. E-mail: jedixon{at}ucsd.edu
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[DOI: 10.1126/science.1126867] |Abstract »|Full Text »|PDF »|Supporting Online Material »
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