Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Logo for

Science 313 (5786): 449-451

Copyright © 2006 by the American Association for the Advancement of Science

CELL SIGNALING:
Protein Kinases Seek Close Encounters with Active Genes

John W. Edmunds1 and Louis C. Mahadevan1*

Signaling kinases may form integral components of transcription complexes, influencing gene expression in an unexpected way.


1The authors are at the Nuclear Signalling Laboratory, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

*E-mail: louis.mahadevan{at}bioch.ox.ac.uk


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
cAMP Enhances Estrogen-Related Receptor {alpha} (ERR{alpha}) Transcriptional Activity at the SP-A Promoter by Increasing Its Interaction with Protein Kinase A and Steroid Receptor Coactivator 2 (SRC-2).
D. Liu, H. Benlhabib, and C. R. Mendelson (2009)
Mol. Endocrinol. 23, 772-783
   Abstract »    Full Text »    PDF »
Mitogen-induced recruitment of ERK and MSK to SRE promoter complexes by ternary complex factor Elk-1.
H.-M. Zhang, L. Li, N. Papadopoulou, G. Hodgson, E. Evans, M. Galbraith, M. Dear, S. Vougier, J. Saxton, and P. E. Shaw (2008)
Nucleic Acids Res. 36, 2594-2607
   Abstract »    Full Text »    PDF »
Microplate-based chromatin immunoprecipitation method, Matrix ChIP: a platform to study signaling of complex genomic events.
S. Flanagin, J. D. Nelson, D. G. Castner, O. Denisenko, and K. Bomsztyk (2008)
Nucleic Acids Res. 36, e17
   Abstract »    Full Text »    PDF »
Cooperative regulation of endogenous cAMP-response element binding protein and CCAAT/enhancer-binding protein in GH-stimulated c-fos expression.
T. X. Cui, R. Kwok, and J. Schwartz (2008)
J. Endocrinol. 196, 89-100
   Abstract »    Full Text »    PDF »
Varicella-Zoster Virus Infection of Human Fibroblast Cells Activates the c-Jun N-Terminal Kinase Pathway.
H. J. Zapata, M. Nakatsugawa, and J. F. Moffat (2007)
J. Virol. 81, 977-990
   Abstract »    Full Text »    PDF »

To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882