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Science 314 (5798): 428-429

Copyright © 2006 by the American Association for the Advancement of Science

SIGNAL TRANSDUCTION:
Protein Synthesis and Oncogenesis Meet Again

Nahum Sonenberg and Arnim Pause

A protein degradation process targets a factor that blocks protein synthesis and inhibits tumor growth. Enhanced degradation of this protein may provide a growth advantage to cancer cells.


The authors are in the Department of Biochemistry and McGill Cancer Centre, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada H3G 1Y6. E-mail: nahum.sonenberg{at}mcgill.ca; arnim.pause{at}mcgill.ca


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