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MEDICINE: Squelching Progesterone's Signal May Prevent Breast Cancer
Results described on page 1467 of this issue of Science suggest that one day it may be possible to use progesterone-blocking drugs rather than surgery to prevent BRCA1-mediated breast cancers. (Read more.)
The editors suggest the following Related Resources on Science sites:
Paula A. Kiberstis (5 December 2006) Sci. STKE2006 (364), tw411.
[DOI: 10.1126/stke.3642006tw411] |Abstract »
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human.
D. C. Howe, N. M. Mount, K. Bess, A. Brown, P. Bungay, K. R. Gibson, T. Hawcock, J. Richard, G. Jones, R. Walley, et al. (2011)
J. Pharmacol. Exp. Ther.
|Abstract »|Full Text »|PDF »