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MEDICINE: Squelching Progesterone's Signal May Prevent Breast Cancer
Jean Marx
Results described on page 1467 of this issue of Science suggest that one day it may be possible to use progesterone-blocking drugs rather than surgery to prevent BRCA1-mediated breast cancers. (Read more.)
The editors suggest the following Related Resources on Science sites:
In Science Magazine
REPORTS
Aleksandra Jovanovic Poole, Ying Li, Yoon Kim, Suh-Chin J. Lin, Wen-Hwa Lee, and Eva Y.-H. P. Lee (1 December 2006) Science314 (5804), 1467.
[DOI: 10.1126/science.1130471] |Abstract »|Full Text »|PDF »|Supporting Online Material »
In Science Signaling
EDITORS' CHOICE
Paula A. Kiberstis (5 December 2006) Sci. STKE2006 (364), tw411.
[DOI: 10.1126/stke.3642006tw411] |Abstract »
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human.
D. C. Howe, N. M. Mount, K. Bess, A. Brown, P. Bungay, K. R. Gibson, T. Hawcock, J. Richard, G. Jones, R. Walley, et al. (2011)
J. Pharmacol. Exp. Ther.
339, 642-653
|Abstract »|Full Text »|PDF »
