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Science 314 (5806): 1689-1690

Copyright © 2006 by the American Association for the Advancement of Science

Purinergic Chemotaxis

Joel Linden

Release of adenosine 5'-triphosphate from immune cells in response to membrane deformation implicates purinergic signaling in cell migration during host defense responses.

The author is in the Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA. E-mail: jlinden{at}

Extracellular ATP mediates the late phase of neutrophil recruitment to the lung in murine models of acute lung injury.
D. Shah, F. Romero, W. Stafstrom, M. Duong, and R. Summer (2014)
Am J Physiol Lung Cell Mol Physiol 306, L152-L161
   Abstract »    Full Text »    PDF »
Extracellular nucleotides inhibit oxalate transport by human intestinal Caco-2-BBe cells through PKC-{delta} activation.
R. Amin, S. Sharma, S. Ratakonda, and H. A. Hassan (2013)
Am J Physiol Cell Physiol 305, C78-C89
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Regulation of Neutrophil Function by Adenosine.
K. E. Barletta, K. Ley, and B. Mehrad (2012)
Arterioscler Thromb Vasc Biol 32, 856-864
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Activation of Adenosine A2A Receptors Inhibits Neutrophil Transuroepithelial Migration.
S. Save, C. Mohlin, R. Vumma, and K. Persson (2011)
Infect. Immun. 79, 3431-3437
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Adenosine Generation and Signaling during Acute Kidney Injury.
J. D. Bauerle, A. Grenz, J.-H. Kim, H. T. Lee, and H. K. Eltzschig (2011)
J. Am. Soc. Nephrol. 22, 14-20
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Role of Extracellular Adenosine in Acute Lung Injury.
T. Eckle, M. Koeppen, and H. K. Eltzschig (2009)
Physiology 24, 298-306
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Purinergic receptors in gastrointestinal inflammation.
V. L. Kolachala, R. Bajaj, M. Chalasani, and S. V. Sitaraman (2008)
Am J Physiol Gastrointest Liver Physiol 294, G401-G410
   Abstract »    Full Text »    PDF »

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