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Science 315 (5812): 607-609

Copyright © 2007 by the American Association for the Advancement of Science

Mitochondrial Longevity Pathways

György Hajnóczky and Jan B. Hoek

A cytosolic protein that translocates into the mitochondria may serve as an integration point for signaling pathways that control longevity and cell death.

The authors are in the Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA. E-mail: gyorgy.hajnoczky{at}, jan.hoek{at}

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