Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Logo for

Science 315 (5814): 952-953

Copyright © 2007 by the American Association for the Advancement of Science

Every Joint Has a Silver Lining

Gary S. Firestein

Therapy directed at a nonimmune cell that is unique to joints could suppress rheumatoid arthritis.

The author is in the Division of Rheumatology, Allergy and Immunology, University of California, San Diego, School of Medicine, 9500 Gilman Drive, MC 0656, La Jolla, CA 92093-0656, USA. E-mail: gfirestein{at}

Acid-sensing ion channel 3 expressed in type B synoviocytes and chondrocytes modulates hyaluronan expression and release.
S. J. Kolker, R. Y. Walder, Y. Usachev, J. Hillman, D. L. Boyle, G. S. Firestein, and K. A. Sluka (2010)
Ann Rheum Dis 69, 903-909
   Abstract »    Full Text »    PDF »
Identification of a Molecular Key to Rheumatoid Arthritis.
Journal Watch (General) 2007, 4
   Full Text »

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882