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Science 315 (5819): 1673-1674

Copyright © 2007 by the American Association for the Advancement of Science

Asymmetry and Immune Memory

Dan R. Littman1 and Harinder Singh2

Asymmetric cell division of lymphocytes ensures that our adaptive immune system maintains a balanced production of two different types of T cells.

1D. R. Littman is in the Howard Hughes Medical Institute, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA. E-mail: littman{at}

2H. Singh is in the Howard Hughes Medical Institute, Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA. E-mail: hsingh{at}

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