MOLECULAR BIOLOGY: How and When the Genome Sticks Together

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Science 317 (5835): 209-210

Erwan Watrin and Jan-Michael Peters

Cells respond to DNA damage by strengthening chromosome cohesion across the entire genome independently of DNA replication.

The authors are at the Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria. E-mail: peters{at}imp.univie.ac.at

REPORTS Postreplicative Formation of Cohesion Is Required for Repair and Induced by a Single DNA Break: Lena Ström, Charlotte Karlsson, Hanna Betts Lindroos, Sara Wedahl, Yuki Katou, Katsuhiko Shirahige, and Camilla Sjögren (13 July 2007)
Science 317 (5835), 242. [DOI: 10.1126/science.1140649]
| Abstract » | Full Text » | PDF » | Supporting Online Material »

REPORTS DNA Double-Strand Breaks Trigger Genome-Wide Sister-Chromatid Cohesion Through Eco1 (Ctf7): Elçin Ünal, Jill M. Heidinger-Pauli, and Douglas Koshland (13 July 2007)
Science 317 (5835), 245. [DOI: 10.1126/science.1140637]
| Abstract » | Full Text » | PDF » | Supporting Online Material »

EDITORS' CHOICE
Molecular Biology
Cohesin Does the Business: Guy Riddihough (17 July 2007)
Sci. STKE 2007 (395), tw257. [DOI: 10.1126/stke.3952007tw257]
| Abstract »

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882

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MOLECULAR BIOLOGY:How and When the Genome Sticks Together