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Science 317 (5845): 1695-1696

Copyright © 2007 by the American Association for the Advancement of Science

How Cells Control Zinc Homeostasis

Dietrich H. Nies

The structure of a transport protein for divalent metal cations sheds light on how metal concentrations in the cell are regulated.

The author is in the Institute for Microbiology, Martin-Luther-University Halle-Wittenberg, 06099 Halle/Saale, Germany. E-mail: d.nies{at}

Zinc Starvation Response in a Cyanobacterium Revealed.
D. H. Nies (2012)
J. Bacteriol. 194, 2407-2412
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Thermodynamics of copper and zinc distribution in the cyanobacterium Synechocystis PCC 6803.
A. Badarau and C. Dennison (2011)
PNAS 108, 13007-13012
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Switch or Funnel: How RND-Type Transport Systems Control Periplasmic Metal Homeostasis.
E.-H. Kim, D. H. Nies, M. M. McEvoy, and C. Rensing (2011)
J. Bacteriol. 193, 2381-2387
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Selective Electrodiffusion of Zinc Ions in a Zrt-, Irt-like Protein, ZIPB.
W. Lin, J. Chai, J. Love, and D. Fu (2010)
J. Biol. Chem. 285, 39013-39020
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The Cation Diffusion Facilitator Gene cdf-2 Mediates Zinc Metabolism in Caenorhabditis elegans.
D. E. Davis, H. C. Roh, K. Deshmukh, J. J. Bruinsma, D. L. Schneider, J. Guthrie, J. D. Robertson, and K. Kornfeld (2009)
Genetics 182, 1015-1033
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Manganese Tissue Dosimetry in Rats and Monkeys: Accounting for Dietary and Inhaled Mn with Physiologically based Pharmacokinetic Modeling.
A. Nong, M. D. Taylor, H. J. Clewell III, D. C. Dorman, and M. E. Andersen (2009)
Toxicol. Sci. 108, 22-34
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Copper Transport Activity of Yeast Ctr1 Is Down-regulated via Its C Terminus in Response to Excess Copper.
X. Wu, D. Sinani, H. Kim, and J. Lee (2009)
J. Biol. Chem. 284, 4112-4122
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