Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Logo for

Science 321 (5889): 648-649

Copyright © 2008 by the American Association for the Advancement of Science

CELL SIGNALING:
"Make and Brake" in Signaling

Aristides G. Eliopoulos

Proteolysis of one component of a receptor-bound complex releases the complex from the cell surface to the cytoplasm to activate kinase signaling.


The University of Crete Medical School and Institute for Molecular Biology and Biotechnology, Foundation of Research and Technology Hellas, Heraklion, Greece. E-mail: eliopag{at}med.uoc.gr


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
CD40 Stimulates a "Feed-Forward" NF-{kappa}B-Driven Molecular Pathway That Regulates IFN-{beta} Expression in Carcinoma Cells.
A. Moschonas, M. Ioannou, and A. G. Eliopoulos (2012)
J. Immunol. 188, 5521-5527
   Abstract »    Full Text »    PDF »
The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas.
P. G. Knox, C. C. Davies, M. Ioannou, and A. G. Eliopoulos (2011)
J. Cell Biol. 192, 391-399
   Abstract »    Full Text »    PDF »

To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882