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Science 322 (5907): 1483-1484

Copyright © 2008 by the American Association for the Advancement of Science

CELL SIGNALING:
Fat Stress and Liver Resistance

Wataru Ogawa1 and Masato Kasuga1,2

Communication among immune and fat cells in adipose tissue and liver hepatocytes underlies the pathogenesis of obesity-related insulin resistance.


1Department of Internal Medicine, Division of Diabetes, Metabolism, and Endocrinology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.

2Research Institute, International Medical Center of Japan, Tokyo 162-8655, Japan. E-mail: kasuga{at}med.kobe-u.ac.jp


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