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Science 323 (5922): 1683-1684

Copyright © 2009 by the American Association for the Advancement of Science

Dangers In and Out

Marco E. Bianchi and Angelo A. Manfredi

The immune system relies on specific signaling molecules to dampen its response to injury while maintaining the capacity to fight infection.

San Raffaele University, Faculty of Medicine, and San Raffaele Scientific Institute, via Olgettina 58, 20132 Milano, Italy. E-mail: bianchi.marco{at}

Dangers Within: DAMP Responses to Damage and Cell Death in Kidney Disease.
D. L. Rosin and M. D. Okusa (2011)
J. Am. Soc. Nephrol. 22, 416-425
   Abstract »    Full Text »    PDF »
Peroxynitrite induces HMGB1 release by cardiac cells in vitro and HMGB1 upregulation in the infarcted myocardium in vivo.
N. Loukili, N. Rosenblatt-Velin, J. Li, S. Clerc, P. Pacher, F. Feihl, B. Waeber, and L. Liaudet (2011)
Cardiovasc Res 89, 586-594
   Abstract »    Full Text »    PDF »
Tumor necrosis factor-{alpha} triggers a cytokine cascade yielding postoperative cognitive decline.
N. Terrando, C. Monaco, D. Ma, B. M. J. Foxwell, M. Feldmann, and M. Maze (2010)
PNAS 107, 20518-20522
   Abstract »    Full Text »    PDF »
A Quarter-Century of Immunotoxicology: Looking Back, Looking Forward.
R. V. House and M. J. Selgrade (2010)
Toxicol. Sci. 118, 1-3
   Full Text »    PDF »
Toll-like Receptor 2 Ligand--Induced Protection against Bacterial Endophthalmitis.
A. Kumar, C. N. Singh, I. V. Glybina, T. H. Mahmoud, and F.-S. X. Yu (2010)
The Journal of Infectious Disease 201, 255-263
   Abstract »    Full Text »    PDF »
HMGB1 loves company.
M. E. Bianchi (2009)
J. Leukoc. Biol. 86, 573-576
   Abstract »    Full Text »    PDF »
Natural ligands for CD33-related Siglecs?.
A. Varki (2009)
Glycobiology 19, 810-812
   Full Text »    PDF »

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