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Science 324 (5924): 192-194

Copyright © 2009 by the American Association for the Advancement of Science

CANCER:
Puzzling Patterns of Predisposition

Patrick J. Pollard and Peter J. Ratcliffe

Mutations in a gene that encodes a metabolic enzyme have been linked to certain brain tumors, but is the gene a tumor suppressor or an oncogene?


Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford OX3 7BN, UK. E-mail: pjr{at}well.ox.ac.uk


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