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Science 328 (5975): 179-180

Copyright © 2010 by the American Association for the Advancement of Science

Medicine

The Microbes Made Me Eat It

Darleen A. Sandoval, and Randy J. Seeley

We share our bodies with a huge array of microorganisms. Many of these live in the intestine and number in the trillions (1). On page 228 in this issue, Vijay-Kumar et al. (2) show that the interaction between our immune system and these gut microbes plays an important role in the metabolic diseases that plague developed countries, with profound implications for the rise in obesity and what can be done about it.

Metabolic Diseases Institute and Department of Internal Medicine, University of Cincinnati, Cincinnati, OH 45237, USA.

E-mail: randy.seeley{at}uc.edu

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
TLR5-Deficient Mice Lack Basal Inflammatory and Metabolic Defects but Exhibit Impaired CD4 T Cell Responses to a Flagellated Pathogen.
S. E. Letran, S.-J. Lee, S. M. Atif, A. Flores-Langarica, S. Uematsu, S. Akira, A. F. Cunningham, and S. J. McSorley (2011)
J. Immunol. 186, 5406-5412
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