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Copyright © 2010 by the American Association for the Advancement of Science
Cell Biology
Opening the Cellular Poison CabinetSeamus J. Martin In complex multicellular organisms, millions of cells die each day as a result of stress, injury, or infection, and as part of the natural cell turnover process that is essential to optimal tissue functioning. Remarkably, cell death in most of these situations is orchestrated by the dying cell itself, a form of cellular suicide called apoptosis (1). On page 1390 in this issue, Ren et al. (2) help to resolve how cells execute this process.
Molecular Cell Biology Laboratory, Department of Genetics, Trinity College, Dublin 2, Ireland. E-mail: martinsj{at}tcd.ie
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882