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Science 289 (5481): 847-849

Copyright © 2000 by the American Association for the Advancement of Science

NEUROBIOLOGY:
Long-Sought Protein Packages Glutamate

Laura Helmuth

Glutamate, one of two neurotransmitters that send the basic "stop" and "go" signals that most other neurotransmitters merely modulate, is called into action wherever rapid-fire excitatory signals are needed--say, for vision or learning. For decades, researchers have been looking for the protein that packages glutamate for express delivery to other neurons. On page 957, researchers report that they've found this elusive transporter, dubbed VGLUT1.


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