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Community

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Directory Contact information for people in the cell signaling community

Clifford Harding
Research Scientist at Case Western Reserve University
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Mark Kirk
Research Scientist at University of Missouri
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Events A current listing of meetings, conferences, and workshops related to cell signaling

Santa Cruz Developmental Biology Meeting
Santa Cruz, CA, United States
August 8 – 11, 2012
Society for the Study of Reproduction 2012 Annual Meeting
State College, PA, United States
August 12 – 15, 2012

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Meeting Reports Highlights from cell signaling meetings and conferences

Systems Biology
Crowdsourcing Network Inference: The DREAM Predictive Signaling Network Challenge
Robert J. Prill, Julio Saez-Rodriguez, Leonidas G. Alexopoulos, Peter K. Sorger, and Gustavo Stolovitzky (6 September 2011)
Sci. Signal. 4 (189), mr7. [DOI: 10.1126/scisignal.2002212]
By aggregating the efforts of the research community, comprehensive and accurate inference of signaling networks may become achievable. Abstract »   Full Text »   PDF »  
Evolution
Sequence, Structure, and Network Evolution of Protein Phosphorylation
Chris Soon Heng Tan (19 July 2011)
Sci. Signal. 4 (182), mr6. [DOI: 10.1126/scisignal.2002093]
Analysis of phosphorylation-based signaling systems provides insight into the evolution of these regulatory molecules. Abstract »   Full Text »   PDF »  

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Presentations Slideshows and notes from talks on cell signaling

Cell Migration
Roles of GRK2 in Cell Signaling Beyond GPCR Desensitization: GRK2-HDAC6 Interaction Modulates Cell Spreading and Motility
Petronila Penela, Vanesa Lafarga, Olga Tapia, Verónica Rivas, Laura Nogués, Elisa Lucas, Rocío Vila-Bedmar, Cristina Murga, and Federico Mayor Jr. (15 May 2012)
Sci. Signal. 5 (224), pt3. [DOI: 10.1126/scisignal.2003098]
GRK2 modulates tubulin acetylation dynamics in an HDAC6-dependent manner to affect epithelial cell spreading and motility. Abstract »   Full Text »   PDF »   Slideshow »  
Development
TGF-β Signaling in Endothelial-to-Mesenchymal Transition: The Role of Shear Stress and Primary Cilia
Peter ten Dijke, Anastasia D. Egorova, Marie-José T. H. Goumans, Robert E. Poelmann, and Beerend P. Hierck (21 February 2012)
Sci. Signal. 5 (212), pt2. [DOI: 10.1126/scisignal.2002722]
The loss of primary cilia is a prerequisite for flow-induced endothelial-to-mesenchymal transition in heart development. Abstract »   Full Text »   PDF »   Slideshow »  

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Forums Open discussions about cell signaling topics and issues

Highlights from Cell Signaling Networks 2011 (27 January 2012)
Nancy R. Gough
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Katsuhiko Mikoshiba Honored by Karolinska Institutet (24 May 2011)
Science Signaling Editors
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E-Letters An online outlet for short, timely comments about specific Science Signaling articles or resources

Ras and Rap GAP Function and GTPase Sequestration in Plexin-Mediated Cell Signaling Mechanisms
Manabu Negishi and Matthias Buck (8 March 2012)
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Noting Two Scientific Inaccuracies
François Leulier et al. (17 February 2012)
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